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Sydney Brenner pioneered the use of the Caenorhabditis elegans nematode worm as a model system primarily to understand the nervous system in the late 1960s.  He chose C. elegans because of its many useful traits that include:

  • a small size) ~1mm long)
  • a 3 day life cycle
  • simple anatomy) 959 cells)
  • transparency
  • store by freezing
  • easy transgenic manipulation

 

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